产品货号：
Z30040
中文名称：
CYP1A2抗体
英文名称：
Anti-CYP1A2 Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-CYP1A2 Antibody |
| 指标别名 | CP12;CP1A2;CYP1A2;CYPIA2;Cytochrome P(3)450;Cytochrome P450 1A2;Cytochrome P450 4;Cytochrome P450 P3;P3 450;P450(PA) |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | WB,IHC |
| 基因名称 | CYP1A2 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | E.coli-derived human CYP1A2 recombinant protein (Position:H185-D320).Human CYP1A2 shares 69.9% and 72.1% amino acid (aa) sequence identity with mouse and rat CYP1A2,respectively. |
| 实际分子量 | 58KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | CYP1A2 (Cytochrome P450,Subfamily I,Polypeptide 2) is a member of the cytochrome P450 mixed-function oxidase system and is involved in the metabolism of xenobiotics in the body.CYP1A2 is a member of the cytochrome P450 superfamily of enzymes.In humans,the CYP1A2 enzyme is encoded by the CYP1A2 gene.CYP1A2 localizes to the endoplasmic reticulum and its expression is induced by some polycyclic aromatic hydrocarbons (PAHs),some of which are found in cigarette smoke.The CYP1A2 gene encodes a P450 enzyme involved in O-deethylation of phenacetin.Ikeya et al.(1989) found that the human CYP1A2 gene spans almost 7.8kb and contains 7 exons.The CYP1A2 gene is mapped on 15q24.1.CYP1A2 accounts for nearly 15% of the cytochrome P450 in the human liver.CYP1A2 displays higher activity in men than in women,and is inhibited by oral contraceptives.Inducers of CYP1A2 include cruciferous vegetables.Cigarette smoking has also been shown to increase CYP1A2 activity.Expression of CYP1A2 appears to be induced by various dietary constituents. |
| Uniprot ID | P05177 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P).*Blocking peptide可以联系我们购买。 |
| 基因名全称 | cytochrome P450,family 1,subfamily A,polypeptide 2 |
| 蛋白名全称 | Cytochrome P450 1A2 |
| 推荐稀释比 | Western blot(WB) 1:500～2000 Immunohistochemistry(Paraffin-embedded Section) 1:50～400 (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
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